Tampa Cruise Guide > Cruise Itineraries > Key West
There are many cruises to Key West from Tampa, Florida. It is included on a variety of itineraries. The complete list of departures is below.
Key West, Florida is the southernmost place in the United States, and is known for a laid-back and wacky attitude.
Key West is compact and walkable, so you can easily explore on your own. Have brunch outdoors at Blue Heaven. Rent a bike. Tour the Hemingway House for a glimpse of life here in the 1930s. Eat key lime pie (Kermit's is one of the top rated). Experience the shops and bars on Duval Street.
Organized shore excursions in Key West include a culinary tour, trolley tour, bike tour, helicopter tour, butterfly conservatory, and the aquarium.
Out on the water you can stand-up paddleboard, catamaran sail, snorkel, kayak, parasail, or snuba.
5-day cruise to Key West on Carnival Cruise Line. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: September 24.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: October 1.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: October 15.
5-day cruise to Key West on Carnival Cruise Line. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: October 27.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: October 29.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: November 12.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: November 26.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: December 10.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2018 departure: December 24.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Santo Tomas de Castilla (Guatemala), Mahogany Bay (Roatan) and Costa Maya (Mexico).
• 2019 departure: January 6.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: January 7.
14-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Puerto Rico, St Thomas, Antigua, St Lucia, Curacao, Aruba and Grand Cayman.
• 2019 departure: January 13.
10-day cruise to Key West on Norwegian Cruise Line. Round-trip from Tampa to Key West (Florida), Tortola (British Virgin Islands), Antigua, St Maarten and Puerto Rico.
• 2019 departure: January 17.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Mahogany Bay (Roatan), Santo Tomas de Castilla (Guatemala) and Costa Maya (Mexico).
• 2019 departure: January 27.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Trujillo (Honduras), Santo Tomas de Castilla (Guatemala) and Costa Maya (Mexico).
• 2019 departure: February 3.
10-day cruise to Key West on Norwegian Cruise Line. Round-trip from Tampa to Key West (Florida), Tortola (British Virgin Islands), Antigua, St Maarten and Puerto Rico.
• 2019 departure: February 7.
14-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Puerto Rico, St Thomas, Antigua, St Lucia, Curacao, Aruba and Grand Cayman.
• 2019 departure: February 10.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: February 18.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Santo Tomas de Castilla (Guatemala), Mahogany Bay (Roatan) and Costa Maya (Mexico).
• 2019 departure: February 24.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Santo Tomas de Castilla (Guatemala), Mahogany Bay (Roatan) and Costa Maya (Mexico).
• 2019 departure: March 3.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: March 4.
14-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Puerto Rico, St Thomas, Antigua, St Lucia, Curacao, Aruba and Grand Cayman.
• 2019 departure: March 10.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: March 18.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Mahogany Bay (Roatan), Santo Tomas de Castilla (Guatemala) and Costa Maya (Mexico).
• 2019 departure: March 24.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Santo Tomas de Castilla (Guatemala), Mahogany Bay (Roatan) and Costa Maya (Mexico).
• 2019 departure: March 31.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: April 1.
7-day cruise to Key West on Holland America Line. Round-trip from Tampa to Key West (Florida), Santo Tomas de Castilla (Guatemala), Mahogany Bay (Roatan) and Costa Maya (Mexico).
• 2019 departure: April 7.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: April 15.
5-day cruise to Key West on Carnival Cruise Line. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: April 27.
5-night cruise to Key West on Royal Caribbean. Round-trip from Tampa to Key West (Florida) and Cozumel (Mexico).
• 2019 departure: April 29.
Cruise Critic has many Key West cruise reviews. The ratings by passengers range from poor to excellent, mainly depending on the ship. Opinions of the island itself are quite high. Visitors have a great time exploring and enjoy things like the aquarium, the Hemingway home, the butterfly conservatory, and key lime pie.
Southern Living offers a plan for one day in Key West. 9 things for a day packed with fun.
View a terrific video of what to do in Key West. It includes tips on places to eat, activities, tours, and bars.